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Arestin Therapy

Treating Adult Gum Disease

Periodontal disease, if left untreated, is a progressive condition that often leads to severe inflammation and tooth loss. Antibiotic treatments can be used in combination with scaling and root planning, curettage, surgery or as a stand-alone treatment in an effort to reduce bacteria before and/or after many common periodontal procedures.

Antibiotic treatments can be found in several different types, including oral forms and topical gels, which are applied directly into the gum pockets. Research indicates that for acute periodontal infection, refractory periodontal disease, prepubertal periodontal disease and juvenile periodontal disease, antibiotic treatments have been incredibly effective.

Antibiotics can be prescribed at a low dose for longer-term use, or as a short-term medication to deter bacteria from re-colonizing.

Arestin Therapy May Be Your Best Course

At CarolinasDentist, we understand that you or someone in your family may need specialized care. Sometimes, advanced treatments are simply the best course of action to take. As your family’s oral health provider, we make sure we have every need covered. This is why we provide Arestin therapy treatment for patients with adult periodontitis (gum disease).

This is a Minocycline antibiotic that comes in mini capsules which are administered into the gums after scaling and root planing. The advantage of the direct delivery of antibiotics to the surfaces of the gums is that the whole body is not affected. Topical gels and direct delivery methods tend to be preferred over their oral counterparts and are extremely effective when used after scaling and root planing procedures.

Noticeable periodontal improvements are typically noticed after systemic or oral antibiotic treatment. Our dentist will incorporate and recommend the necessary antibiotic treatments as necessary for the healing of your periodontal condition.

We also recommend these at-home treatments to help prevent advanced gum disease:

  • Fluoride toothpaste with the American Dental Association seal
  • Toothbrush with soft bristles (firmer bristles can wear away enamel and damage gums)
  • Electric toothbrush (particularly people with mobility issues may find this easier to use)
  • Dental floss holders (plastic devices that hold a short length of floss)
  • Interdental brushes (these brushes are designed to clean between your teeth in areas where a toothbrush can’t reach)

Don’t put off treatment; the goal is to keep the bacterial infection from progressing and return to healthy gums. Reach out to the CarolinasDentist office near you to discuss if Arestin is the treatment you need to treat your gums.

At CarolinasDentist, our compassionate, highly skilled dentists are dedicated to making sure you enjoy excellent oral health and a return to healthy gums. No matter what you need or what office near you that you visit, you’ll be in good hands. Reach out to us today to begin your journey to your best oral health!

Frequently Asked Questions

Yes, gum disease can spread if left untreated. It begins with localized inflammation in the gums and can progress to the surrounding tissues, including the bone and ligaments that support the teeth. Additionally, bacteria from gum disease can enter the bloodstream, potentially impacting overall health by increasing the risk of conditions like heart disease or diabetes. Early treatment and good oral hygiene can prevent its spread.

Yes, you can brush your teeth after receiving Arestin, but avoid brushing near the treated area for 12 hours. This precaution helps ensure the antibiotic stays in place and delivers its full benefits. Flossing and using interdental cleaners should also be avoided for 10 days near the application site to prevent dislodging the medication.

Arestin is applied as a fine powder that adheres to the gum tissue, so it is unlikely to fall out under normal circumstances. However, improper brushing, flossing, or eating hard or sticky foods too soon after application may dislodge it. To ensure it remains effective, follow our post-treatment guidelines closely and attend any scheduled follow-up visits.

Arestin can be used multiple times, depending on the severity of gum disease and your response to treatment. Our team may recommend repeat applications during scaling and root planing procedures or periodontal maintenance visits if necessary. The frequency of use is tailored to your individual oral health needs, as part of a comprehensive plan to manage gum disease and maintain healthy gums over time.

You may also be a good candidate for Perio Protect®, a non-invasive periodontal treatment that helps manage gum disease using custom-made prescription trays and a targeted antibacterial gel. These trays are designed to fit comfortably over your teeth and deliver medication deep below the gumline, reaching areas that brushing, flossing, and even professional cleanings may miss. Worn for just a few minutes each day at home, the trays allow the medication to penetrate periodontal pockets and reduce harmful bacteria over time.

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Andrew Callender

Andrew Callender

Regional Director of Operations

Andrew Callender was born and raised in Denver, Colorado, and serves as one of our Regional Directors of Operations at CarolinasDentist, focusing on our Western NC and Charlotte regions. He joined the leadership team in 2025 and earned his degree from Western Colorado University. Andrew brings over 12 years of experience in dentistry, including more than 10 years of progressive leadership in healthcare operations and three years serving as a Regional Director of Operations. He relocated to North Carolina in 2023 and has quickly made an impact across the region.

Andrew is passionate about delivering outstanding patient care through operational excellence. He is committed to fostering an environment that aligns with CarolinasDentist’s values and culture while leveraging diverse perspectives and experiences to support team success and growth. His leadership style is rooted in collaboration, consistency, and continuous improvement.

Outside of work, Andrew enjoys spending time with his wife and their four children. He’s an avid golfer and also enjoys walking his lab, Harper—making the most of his time outdoors with family and fresh air.

Nate Bunyak

Nate Bunyak

Regional Director of Operations

Nate Bunyak brings a little bit of Pittsburgh grit and a whole lot of energy to everything he does. He is one of the Regional Director of Operations at CarolinasDentist focusing on our Triangle region, joining the team in 2026. Originally from Pittsburgh, PA, Nate graduated from Indiana University of Pennsylvania (IUP) with a degree in Marketing and Management—and has been putting both to work ever since. Three years ago, he traded in steel city winters for North Carolina sunshine—and hasn’t looked back.

When he’s not working, Nate is all about family life with his wife, Melissa, and their three kids—Bryce, Molly, and Connor. Whether cheering on their activities, exploring the outdoors, or simply embracing the joyful chaos of a busy household, he makes the most of every moment with his family.

An avid hiker and nature enthusiast, Nate loves adventures that combine fresh air, beautiful views, and lasting memories. That same adventurous, positive spirit carries into his work—he’s driven, all-in, and always ready to take on what’s next.

Jenna Holland

Jenna Holland

Regional Hygiene Director

Jenna Holland is a Fayetteville native and serves as Regional Hygiene Director, joining the leadership team in 2026. She began her career with CarolinasDentist in June 2016 as a dental hygienist in the Fayetteville office after graduating from Fayetteville Technical Community College. Over the years, she has grown within the organization, building strong relationships with both patients and team members while staying rooted in her passion for patient care.

Jenna is deeply committed to promoting overall well-being through oral health and believes in the powerful connection between a healthy smile and a healthy body. In her leadership role, she especially loves mentoring and coaching hygienists, helping them grow in confidence, strengthen their clinical skills, and develop into exceptional providers. She takes pride in supporting her team and fostering an environment of continuous learning and encouragement.

Her best advice for patients is simple: stay consistent with routine check-ups and cleanings to maintain optimal health. Outside of the office, Jenna enjoys traveling—especially to warm, tropical destinations—and is engaged to her high school sweetheart, adding a personal touch to her passion for caring for others.